Episodes

Cannabis seed laws are changing, and the consequences could reshape home grow, hemp, cannabis breeding, and the future of plant genetics in the United States. In this episode of the Bioactive Podcast, Dr. Riley Kirk sits down with longtime organic farmer, seed breeder, and policy advocate Jim Riddle to explain the proposed federal seed ban, why cannabis seeds are being caught up in new legislation, and what it could mean for growers, breeders, researchers, and consumers. Drawing from over four...

Cannabis tissue culture, plant genetics, micropropagation, and pathogen testing are transforming modern cultivation. In this episode of the Bioactive Podcast, Dr. Riley Kirk is joined by Dr. Nathan Johnson, President & CEO of Verne Bio, for a fascinating deep dive into one of the most powerful—and misunderstood—tools in cannabis cultivation. Together they explore how tissue culture is helping preserve elite cannabis genetics, eliminate plant pathogens, improve cultivation consistency, and solve...

Dr. Riley Kirk welcomes Dr. Anna Schwabe to the Bioactive Podcast for a deep dive into cannabis genetics, cultivar identity, plant chemistry, and the challenges of making sense of cannabis in a rapidly evolving industry. As two cannabis scientists get thoroughly nerdy, they explore the relationship between genetics and chemical expression, why cultivar names matter, and what science can and cannot tell us about predicting cannabis effects. Drawing from years of research in cannabis genomics, ch...

In this episode of the Bioactive Podcast, Dr. Riley Kirk is joined by Brandon Rust, founder and CEO of FulCrop Sciences, for a fascinating conversation about the hidden biological systems that drive plant health and productivity. Brandon shares insights from years of cultivation experience, explaining how modern growing practices have shifted away from natural ecosystem processes and why rebuilding biological balance may be one of the most important steps for improving plant performance and long...

Dr. Riley Kirk welcomes Kyle Boyar to the Bioactive Podcast for an in-depth conversation on cannabis testing, mycotoxins, analytical chemistry, biohacking, and the evolving cannabis industry. Drawing from over a decade of experience in cannabis science, Kyle shares insights from his work across leading cannabis testing laboratories, academic institutions, and regulatory spaces. The discussion explores how cannabis testing has evolved over the years, the importance of accurate lab data, and the r...

Dr. Riley Kirk welcomes Tessa Dattilo to the Bioactive Podcast to break down what it really means to be a budtender and how cannabis education translates to real-world consumer experiences. With nearly a decade in the cannabis industry, Tessa shares insights from the frontlines—helping patients and customers navigate products, understand cannabinoids and terpenes, and make informed decisions in an increasingly complex market. They explore the science behind how different cannabis products affec...

On this episode, Dr. Riley Kirk welcomes Dr. Emily Gogol to the Bioactive Podcast to discuss the science, cultivation, and accessibility of cannabis from both a research and real-world growing perspective. Drawing from her background in biomedical science and her work leading Infinite Tree and Grow It From Home, Emily shares her journey from infectious disease research into cannabis farming, and how she applies data-driven methods to breeding, field trials, and terpene selection. They explore th...

On this episode of the Bioactive Podcast, Dr. Riley Kirk is joined by Dr. Codi Peterson and Megan Mbengue to discuss their newly published paper on Cannabinoid Hyperemesis Syndrome (CHS). Drawing from their recently published research and clinical experience, they explore what CHS is, how it presents, and why it is often misunderstood or misdiagnosed. The conversation covers early warning signs, the prodromal phase, and the severe symptoms patients experience, including the challenges faced in e...

Dr. Riley Kirk welcomes Nikki Lawley to the podcast to discuss the transformative role of medical cannabis in managing traumatic brain injury (TBI), sharing her powerful personal journey alongside practical insights into cannabis as medicine. They cover topics such as the immediate and long-term symptoms of TBI, the challenges of navigating traditional healthcare systems, and the limitations of pharmaceutical treatments. Additionally, they explore how cannabis became a turning point in Nikki’s r...

There are all sorts of misconceptions about coffee — that it dehydrates you, that it’s bad for your heart, or that caffeine is the only thing happening in the cup. Dr. Riley Kirk welcomes coffee scientist Dr. Steven Helschien, widely known as “Dr. Coffee,” for a fascinating conversation exploring the chemistry, health effects, and cultural significance of one of the world’s most widely consumed psychoactive plants: coffee. With a background in chemistry and extensive experience in coffee educat...

Dr. Riley Kirk welcomes Dr. Harold Han, Chief Science Officer and Co-Founder of Vertosa to explore the fascinating world of the science powering modern cannabis beverages and infused products. Known in the industry as “The Happy Chemist,” Dr. Han explains how emulsion technology solves the classic oil-and-water problem that makes cannabinoids difficult to incorporate into drinks. The conversation breaks down how water-compatible cannabinoids are created, why droplet size and consistency matter f...

In this episode of the Bioactive Podcast, Dr. Riley Kirk welcomes cannabis attorney and legalization advocate Tom Howard to unpack the complexities of cannabis law and regulation in the United States. Drawing on more than 15 years of experience, Tom shares how he helps clients navigate licensing and application processes for dispensaries and cannabis businesses across multiple states. Together, they explore how state-by-state regulatory systems function, the challenges of securing permits, and t...

In this episode of the Bioactive Podcast, Dr. Hemant Bid joins Dr. Riley Kirk discussing the often-overlooked world of acidic cannabinoids aka Raw or Unactivated cannabinoids, such as CBGA, THCA, and CBDA. He shares his extensive background in cannabis research and education, emphasizing the therapeutic potential of these compounds, which are non-psychoactive and interact with various non-cannabinoid targets in the body. The conversation also delves into extraction techniques for preserving thes...

In this episode of the Bioactive Podcast, Dr. Riley Kirk shares a 2025 year-in-review and announces exciting news about teaching a cannabis chemistry and pharmacology course at Vermont State University next Spring. Riley then dives into a Q&A packed with highly requested cannabis education topics, answering real listener questions about nanoemulsification safety, whether CBN truly helps with sleep, and the pros and cons of dabbing concentrates. She also breaks down how to talk to family about c...

Dr. Riley Kirk has Jordan River on the podcast to discuss the intricacies of indoor cannabis cultivation, sharing personal experiences and insights on various aspects of growing. They cover topics such as the challenges of transitioning plants from outdoor to indoor environments, the importance of consistency in care, effective watering techniques, and the management of temperature and light. Additionally, they delve into soil health, pest management, and the processes of harvesting, drying, and...

In this episode of the Bioactive Podcast, Dr. Riley Kirk and Dr. Miyabe Shields dive into the world’s largest study on infused cannabis beverages, exploring how cannabinoid-based drinkables are transforming wellness, social drinking culture, and public health. They sit down with Tyler and Kevin from MoreBetter who designed and executed this groundbreaking study. They break down the study design, participant demographics, and key findings, including data showing a reduction in alcohol consumptio...

Alex Eckman shares his journey in the cannabis industry, from being a medical patient to pursuing a degree in cannabis chemistry at Lake Superior State University. He discusses the evolution of cannabis education, the importance of research, and his findings on vape carts and microplastics. Alex also addresses the challenges facing the Michigan cannabis market and his aspirations for the future, emphasizing the need for education and informed decision-making in the industry. Chapters 00:00Intr...

CONTENT WARNING: IF YOU HAVE STRUGGLED WITH A DIFFICULT BIRTH EXPERIENCE THIS STORY MAY NOT BE BENEFICIAL TO LISTEN TO Dr. Riley Kirk shares her postpartum journey, discussing her high-risk pregnancy due to ICP, the challenges of early induction, and her return to cannabis use for mental well-being. She emphasizes the importance of self-advocacy, mental health, and the healing power of cannabis, while also expressing gratitude for her supportive community. 00:00 Introduction and Pregnancy Upda...

Dr. Riley Kirk welcomes international cannabis consultant, researcher, and author Russ Hudson to explore the fascinating world of flavonoids—an often overlooked but powerful group of compounds found in cannabis and everyday foods. In this episode, Russ shares his journey from the underground cannabis market to scientific research, and together they break down what flavonoids are, how they impact plant color, health, and resilience, and why they matter for human nutrition and wellness. Discover t...

In part two of Dr. Riley Kirk's conversation with Dr. Janice Makela, MD, they discuss cannabis use among the elderly for sleep and mental health matters.

Dr. Janice Makela discusses Cannabis and Geriatric Care: Dosing, Consumption, and Special Health Considerations

In this episode of the Bioactive Podcast, I sit down with Jürgen Bickel, Managing Director and Co-Founder of STORZ & BICKEL, the legendary German company behind the Volcano, Mighty, Venty and Crafty vaporizers. We dive deep into: - What dry herb vaping is and how it works - Why vaporizing cannabis may be a healthier option compared to smoking - The science behind medical-grade vaporizers and what makes STORZ & BICKEL devices trusted by patients and professionals worldwide - Which herbs (beyond ...

Host Dr. Riley Kirk speaks with Devin Melnyks about his experience navigating both the grower and tech start up spaces in the cannabis industry, and his new app called HiNote.ai.

This week we are headed to Germany, this podcast was recorded at the world's largest cannabis expo called Mary Jane Berlin. I had the opportunity to jointly host and record a podcast with Lauren Avenius, the CEO of Node Labs. She is doing some ground breaking work with cannabis breeding and genetics and is doing an amazing job connecting people across the industry. Her work also encompasses other companies like Four20Pharma and Compound Genetics. This conversation covers everything from strain ...