In this episode of the Bioactive Podcast, Dr. Riley Kirk sits down with cannabis research scientist Ben Cleary to unpack groundbreaking research published in Scientific Reports examining THC variability in cannabis flower and what it means for consumers, cultivators, laboratories, and regulators.
If you've ever wondered why the same strain can feel different from batch to batch—or why chasing the highest THC percentage often leads to disappointment—this conversation explains the science behind it.
Ben shares how his team's research demonstrates the natural variability of THC within a single cannabis plant and why reporting one THC percentage may not accurately represent what consumers actually purchase. Together, Riley and Ben discuss the future of cannabis labeling, range-based THC reporting, lab testing variability, terpene science, chemical diversity, and how better education can improve purchasing decisions and consumer trust.
They also explore why aroma may be a better guide than THC percentage alone, how Canada's cannabis industry is beginning to implement THC ranges, the role of laboratory variation in cannabis testing, and what future cannabis packaging could look like as science continues to evolve.
Whether you're a cannabis consumer, cultivator, scientist, budtender, regulator, or simply curious about how cannabis testing really works, this episode offers an evidence-based look at one of the industry's biggest conversations.
CHAPTERS:
00:00 Dispensary Label Problem
01:07 Meet the Host and Guest
01:56 Inside Village Farms Scale
03:48 Why Study THC Variability
05:30 What a Single Number Misses
08:11 Where THC Varies on Plants
10:07 Ranges Over Single Values
12:01 Smell and Shop Experience
13:06 How to Set THC Ranges
19:59 Beyond THC Terpenes CBD
23:48 Lighting Scale and Validity
31:24 Sampling Protocol Shortcuts
34:15 Lab Testing Trust Issues
36:04 Variability Triad Explained
37:48 Beyond THC Toward Quality
39:48 Industry Adoption Call
41:40 Why Village Farms Cares
43:57 Next Research Frontiers
46:04 Real World Data Models
47:35 Cannabis Science Community
49:54 Clinicians Knowledge Gap
53:42 Chemical Diversity Score
57:07 Simplifying Labels for Consumers
58:32 Where to Follow Ben
01:00:33 Closing Thanks and BC Invite
Read the Scientific Reports paper discussed in this episode:
https://www.nature.com/articles/s41598-025-06962-2
Connect with Ben Cleary
LinkedIn: https://www.linkedin.com/in/ben-cleary-746b00172/
Village Farms International: https://villagefarms.com/
Want Exclusive Content and ad-free episodes?
Join the Bioactive Patreon community for as little as $1/month to ask guests your burning
questions, access exclusive content, and connect with Dr. Kirk one-on-one.
www.Patreon.com/Cannabichem
Don’t forget to like, subscribe, and hit the notification bell for more expert insights into
cannabis science, plant biology, and more!
Sign Up for Emails!
www.AppliedPharmacognosy.org
Keep up with Dr. Riley Kirk:
https://www.bioactivepodcast.com/
https://www.youtube.com/@cannabichem
https://instagram.com/cannabichem
https://www.appliedpharmacognosy.org/